Preliminary Experience in the Treatment of Pearly Penile Papules with Holmium: YAG laser

Introduction: Pearly penile papules are common, benign lesions that may be a source of concern and embarrassment for many men. Therapeutic options such as electrodessication, shave excision, cryotherapy, and CO2 laser ablation have demonstrated variable degrees of efficacy, and may result in scarring and hypopigmentation. Holmium: YAG lasers are widely available to most urologists, and have operational characteristics that make them safe for treating cutaneous lesions. Aim: We herein describe three Caucasian males with extensive pearly penile papules, treated using the Holmum: YAG laser. Methods: Following treatment, patients were followed for 8, 13, and 16 months. Results: All patients were treated in the outpatient setting, had an uneventful recovery, did not require complex wound care, and did not develop scarring or hypopigmentation. All three patients were satisfied with their results, which proved to be aesthetically flawless. Conclusions: Holmium: YAG laser ablation appears to be a safe and effective option for treatment of pearly penile papules in Caucasian men. Further experience is warranted, particularly in men with different skin colors and tones.